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For measurements samples were diluted in filtered PBS to a final concentration of 1 mg/ml

GHK-Cus documented NGF stimulation appears to sit within its broader gene expression modulation signature rather than representing a direct receptor interaction, which is mechanistically coherent with the transcriptomic reactivation data showing GHK-Cu shifting aging gene expression profiles toward younger patterns (PMID: 25904764)

135 PGC-1, which shares structural and functional similarities with PGC-1, also promotes mitochondrial biogenesis

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