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Blood pressure: mild transient effects at high doses in animal models

Sheetz MJ, King GL

A portion of the kidney, weighing about 100 mg, was cut in cross-section and stored in RNAlater for gene expression analysis

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These targeted microbubbles specifically bind to vascular endothelial cells expressing VCAM-1 in the early stages of IRI, and changes in their ultrasound signals show good correlation with serum and tissue pathological biomarkers [144]