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The elevation of testicular IGF1 through prepubertal administration of rhGH could thus evoke the early onset of sexual maturation without increasing circulating LH levels, resembling GIPP

Although current data are limited, emerging evidence suggests an increased risk of breast cancerbut a decreased risk of prostate canceramong transgender women receiving GAHT, compared to age-matched cisgender men (369)de Blok CJM, et al

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Vitamin C is also associated with enhancing tissue development and replacement