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(54) found that administering GIPR antagonist to healthy humans reduced postprandial insulin secretion and increased glucose excursions more than administering GLP-1R antagonist (GLP-1RA), indicating that endogenous GIP may play a more significant role in stimulating insulin secretion and reducing postprandial plasma glucose excursions compared to endogenous GLP-1

Probiotics can help stabilize the gut microbiome, reduce inflmmation and improve the gut barrier

Interaction between Cannabis and GLP-1 Inhibitors Interaction between Cannabis and GLP-1 Inhibitors Functional Gastroparesis Can Cause Severe Distress GLP-1 receptor agonists and cannabinoids both slow gastrointestinal motility, so concurrent use can meaningfully increase the risk of delayed gastric emptying, gastroparesis-like symptoms, and nauseavomiting syndromes in susceptible patients

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For individuals with type 2 diabetes or non-diabetic hyperglycaemia (pre-diabetes), NICE recommends structured exercise programmes as part of comprehensive management

If thats the case, then antifungals arent needed