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Personalized Eating Strategies with Genetic Testing Individual responses to semaglutide and food choices vary significantly based on genetic factors affecting appetite regulation and metabolism

SPL UNCLASSIFIED SECTION Add-on to metformin with or without SGLT2 inhibitor SURPASS-3 (NCT03882970) was a 52-week open-label trial that randomized 1444 adult patients with type 2 diabetes mellitus with inadequate glycemic control on stable doses of metformin with or without SGLT2 inhibitor to the addition of subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, MOUNJARO 15 mg once weekly, or insulin degludec 100 units/mL once daily

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Psychosis or Schizophrenia: Stimulants can worsen symptoms like hallucinations or paranoia in people with these conditions

The addition of metformin appears most beneficial in patients with elevated fasting insulin or HOMA-IR scores above 3