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It is used in conditions that involve oxidative stress, from Parkinsons disease to chronic obstructive pulmonary disease, and some cancer protocols use it to protect healthy cells from the side effects of chemotherapy and radiation

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Glutamate is also needed for the production of glutathione

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Consistent with our expectations, NRF2 depletion promoted the cell cycle and proliferation of keratinocytes

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To this end, we performed a preclinical study in 18-mo-old male and female mice treated with vehicle or an IGF-1R mAb (L2-Cmu, Amgen Inc), and determined effects on aging outcomes

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